Alexandra Joseph, PhD is an R&D leader with over 20 years of experience advancing programs from discovery through commercialization and driving research, clinical and commercial strategies in big pharma and biotech. Alexandra has worked across a variety of indications including oncology, autoimmunity and inflammation, neurology and rare disease. Dr. Joseph held leadership roles of increasing responsibility during her 17-year tenure at Sanofi where she directed drug discovery and development, including two commercialized medicines. As Head of Scientific Portfolio Management and Operations for Immunology and Inflammation Research at Sanofi, she established the Immunology Research Organization and oversaw the discovery pipeline that delivered seven clinical candidates including Frexalimab. Prior to joining Photys, she was Executive Vice President of Biology at Exo Therapeutics, Vice President of Research at ImmuneID and Head of Translational Research at Kiniska. At Kiniksa, Alexandra developed and executed translational research strategies for Vixarelimab, Mavrilimumab and Abiprubart across autoimmune and inflammatory diseases. Dr. Joseph received her Ph.D. in Immunology from Tufts University Graduate School of Biomedical Science and completed her post-doctoral training at the Immune-Mediated Disease Institute at Harvard Medical School. She received a B.A. in Biology from Santa Clara University in California.